Not Just Lyme: Powassan Virus

Most people are familiar with Lyme disease as one of the most common tick-borne illnesses in the United States. However, there are several other illnesses that can be transmitted to humans by ticks. One potentially deadly tick-borne illness is Powassan virus, which although rare, the number of reported cases has increased in recent years. 33 severe cases of Powassan virus were reported in 2017, which compared to the 2 reported cases in 2008 is an alarming increase.

In Sussex County in 2019, there were 2 potential cases of Powassan virus. One person improved with antibiotics, making it unclear if Powassan virus was the main issue since viruses cannot be cured with antibiotics. The second person unfortunately passed away, but it is unclear whether the virus was the main cause of death since the patient had other medical issues.

Powassan virus is spread to humans through the saliva of an infected tick. It is particularly insidious because there are very few symptoms, no cure, and many infected patients require hospitalization. The best preventative measures are by avoiding contact with ticks to decrease your chances of becoming infected.


Powassan virus attacks the central nervous system. Although many people do not exhibit any symptoms while the virus incubates, some symptoms of altered brain function include

  • Fever
  • Headache
  • Vomiting
  • Weakness and loss of coordination
  • Confusion
  • Speech difficulty  
  • Encephalitis, or inflammation of the brain
  • Meningitis, or inflammation of the membranes that surround the brain and spinal cord
  • Seizures

Approximately 10% of encephalitis cases caused by Powassan virus are fatal. Survivors of Powassan virus may have permanent neurological symptoms.


There are currently no medications or vaccines for Powassan virus. People that are severely infected and are exhibiting symptoms must be evaluated by a healthcare professional and may need to be hospitalized. Treatment in the hospital may include intravenous fluids, medications to reduce swelling in the brain, and respiratory support.


Prevention is the best way to avoid infection.

Avoid walking through grassy, wooded areas, especially in the spring and early summer. If you must be in these areas, always check yourself for ticks afterwards. Some important places to check for ticks are

  • In the hair
  • In and around ears
  • Inside the belly button
  • Under the arms
  • Between the legs
  • Behind the knees
  • Around the waist

Using EPA-registered insect repellents containing DEET can aid in keeping ticks off of your body and clothing. Wearing light-colored clothing can be useful to spot ticks.

It is also important to check your pets regularly for ticks, as Powassan virus-carrying ticks can be found on pets, and later bite the owner.

For frequently asked questions about Powassan virus, please refer to the Center for Disease Control and Prevention’s webpage.